ARA-290

ARA-290 is a synthetic peptide derived from erythropoietin’s helix-B surface region, designed to selectively activate the EPOR-CD131 (Innate Repair Receptor) complex. This pathway is studied for its tissue-protective and anti-inflammatory effects, without stimulating erythropoiesis. Research suggests ARA-290 plays a key role in cellular stress response, nerve repair, and endothelial protection, making it relevant for models involving metabolic stress and neuroprotection.